Largemouth bass anglers have their best success on Lake Buchanan during the spring and fall months. The area from Beaver Creek to the Colorado River is usually stained. This keeps the largemouth bass shallow regardless of the water temperature. In the lower section of the reservoir where the water remains clear, topwater lures, metal flake willow leaf spinnerbaits and shallow to medium depth crankbaits work well along rocky banks. When the reservoir is at full pool or higher, flipping boat docks, flooded willows and laydown logs with jigs and plastic worms can be productive.

Starting in February, white bass and striped bass begin their annual spawning run up the Colorado River. Anglers should concentrate their efforts from Beaver Creek into the Colorado. Information on fishing the river above Lake Buchanan is available in "Fly Fishing the Texas Hill Country" by B.L. "Bud" Priddy. Productive lures for white bass include twister tail jigs, small hair jigs, small crankbaits, and small topwaters. Live bait fishing with minnows is also productive. For stripers, live shad fished with a carolina rig type set up on the bottom on humps and along dropoffs is almost always productive. Topwater fishing is good in late spring and again in the fall. Anglers should concentrate on main-lake points and humps. When birds are sighted working schools of shad, this usually indicates stripers or white bass chasing bait just below the surface. During the heat of the summer anglers may have to use downriggers to effectively target striped bass. White or yellow bucktail jigs and trailers work well behind downriggers. Electronics can help locate main-lake structure for this type of fishing. Anglers should set their downrigging balls just above the thermocline depth, usually 20-30 feet.

Catfish anglers can find channel, blue, and flathead catfish throughout the reservoir, with blues dominating the fishery. Stinkbaits and cutbaits work well for the blues and channel cats, while live bait is preferred by large flathead catfish.